C-reactive protein and colorectal cancer

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Commentary C-reactive protein and colorectal cancer

There is no doubt that colorectal cancer poses a significant clinical burden. According to Cancer Research UK, there are around 35000 new cases of large-bowel cancer in the UK annually, making it the second most common malignancy in women, and the third most common in men. In 2002, there were 16 220 deaths from the disease. Overall, around 40% of sufferers survive for 5 years. Early diagnosis l...

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C-reactive protein and colorectal cancer mortality in U.S. adults.

BACKGROUND Chronic inflammation has been associated with colorectal cancer. Prediagnostic levels of C-reactive protein (CRP), a highly sensitive marker of inflammation, have been weakly associated with increased colorectal cancer incidence, but few data are available examining its relationship with colorectal cancer mortality. METHODS In the Third National Health and Nutrition Examination Sur...

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Evaluation of preoperative elevation of serum c-reactive protein as an indicator for prognosis of colorectal cancer

  Abstract   Background : Cancer has not been elucidated in colerectal site. C-reactive protein   (CRP) is a product synthesized in hepatocytes and has been reported to be up-regulated   by such proinflammatory cytokines as interleukin-1 (IL-1), interleukin-6 (IL-6),   and tumor necrosis factor (TNF). The significance of a preoperative serum elevation   was evaluated using CRP as a predictive i...

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Prognostic Value of C - reactive Protein and Procalcitonin Levels in Predicting Anastomotic Leakage after Colorectal Resection in Mazandaran Province

Background and purpose: Colorectal resection is used for various diseases and leakage in an anastomosis is one of its complications. Some studies confirmed the predictive effects of C-reactive protein (CRP) and procalcitonin markers leakage in anastomosis. This study aimed to investigate the prognostic value of CRP and procalcitonin in predicting anastomotic leakage in elective colorectal surge...

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ژورنال

عنوان ژورنال: QJM

سال: 2006

ISSN: 1460-2725,1460-2393

DOI: 10.1093/qjmed/hcl056